
Join our newsletter for 10% off your first order, plus early access to launches and The Noble Program updates.
Earn Loyalty points. Learn More
We stand by our science. Love it, or return it. Our Guarantee
Complimentary 2-Day Shipping in the US.
Need assistance? Talk to our skincare concierge. here



Restores firmness/ elasticity/ volume

Treats Hyperpigmentation

Suitable for sensitive skin
Reduces Redness
Reduces Fine Lines & Wrinkles
8 + 60 doses ($635 value)
Harness your skin's chronobiological cycle of defense during the day and renewal overnight with this powerful duo designed to shield and renew the skin. With Noble Panacea’s revolutionary OSMV™ Technology, the Multi-Defense Cream SPF 50 and the Overnight Chronobiology Peel and work in perfect synergy to shield your skin from UV, blue, infrared light, dust and pollutants during the day, and subsequently exfoliate to correct signs of skin damage at night.
Overnight Chronobiology Peel Refill (8 doses) – A luxurious overnight treatment that works in harmony with your skin’s natural circadian rhythm to exfoliate, renew, and restore. Powered by a blend of AHAs and BHA, this chemical peel treatment gently accelerates skin renewal, improving skin texture and reducing the appearance of scarring, hyperpigmentation and wrinkles while you sleep. Enhanced with OSMV™ Technology, the peel delivers active ingredients at the optimal time in sync with the skin's overnight circadian rhythm. As the final stage, it releases a blend of gotu kola to calm and soothe, eliminating the need for a neutralizing agent. In the evening, apply the Overnight Chronobiology Peel after cleansing. Use 1-2 times per week and allow the formula to dry for 10 minutes before applying a night cream. The micro-dosed release, made possible by our patented OSMV™ Technology, means no downtime is required the next day.
Multi-Defense Cream SPF 50 (60 doses) – A high-performance 100% mineral SPF 50 that protects against sun damage whilst working to correct existing signs of photoaging including hyperpigmentation, fine lines and wrinkles. The Multi-Defense Cream SPF 50 is the first SPF activated by UV light, designed to deliver protection when your skin needs it most. Apply the Multi-Defense Cream every morning as the final step in your skincare routine to keep your skin safe, hydrated, and luminous throughout the day.








Restores firmness/ elasticity/ volume

Treats Hyperpigmentation

Suitable for sensitive skin
Reduces Redness
Reduces Fine Lines & Wrinkles
8 + 60 doses ($635 value)
Harness your skin's chronobiological cycle of defense during the day and renewal overnight with this powerful duo designed to shield and renew the skin. With Noble Panacea’s revolutionary OSMV™ Technology, the Multi-Defense Cream SPF 50 and the Overnight Chronobiology Peel and work in perfect synergy to shield your skin from UV, blue, infrared light, dust and pollutants during the day, and subsequently exfoliate to correct signs of skin damage at night.
Overnight Chronobiology Peel Refill (8 doses) – A luxurious overnight treatment that works in harmony with your skin’s natural circadian rhythm to exfoliate, renew, and restore. Powered by a blend of AHAs and BHA, this chemical peel treatment gently accelerates skin renewal, improving skin texture and reducing the appearance of scarring, hyperpigmentation and wrinkles while you sleep. Enhanced with OSMV™ Technology, the peel delivers active ingredients at the optimal time in sync with the skin's overnight circadian rhythm. As the final stage, it releases a blend of gotu kola to calm and soothe, eliminating the need for a neutralizing agent. In the evening, apply the Overnight Chronobiology Peel after cleansing. Use 1-2 times per week and allow the formula to dry for 10 minutes before applying a night cream. The micro-dosed release, made possible by our patented OSMV™ Technology, means no downtime is required the next day.
Multi-Defense Cream SPF 50 (60 doses) – A high-performance 100% mineral SPF 50 that protects against sun damage whilst working to correct existing signs of photoaging including hyperpigmentation, fine lines and wrinkles. The Multi-Defense Cream SPF 50 is the first SPF activated by UV light, designed to deliver protection when your skin needs it most. Apply the Multi-Defense Cream every morning as the final step in your skincare routine to keep your skin safe, hydrated, and luminous throughout the day.

Join our newsletter for 10% off your first order, plus early access to launches and The Noble Program updates.

Earn Loyalty points. Learn More
We stand by our science. Love it, or return it. Our Guarantee
Complimentary 2-Day Shipping in the US.
Need assistance? Talk to our skincare concierge. here






Restores firmness/ elasticity/ volume

Treats Hyperpigmentation

Suitable for sensitive skin
Reduces Redness
Reduces Fine Lines & Wrinkles
8 + 60 doses ($635 value)
Harness your skin's chronobiological cycle of defense during the day and renewal overnight with this powerful duo designed to shield and renew the skin. With Noble Panacea’s revolutionary OSMV™ Technology, the Multi-Defense Cream SPF 50 and the Overnight Chronobiology Peel and work in perfect synergy to shield your skin from UV, blue, infrared light, dust and pollutants during the day, and subsequently exfoliate to correct signs of skin damage at night.
Overnight Chronobiology Peel Refill (8 doses) – A luxurious overnight treatment that works in harmony with your skin’s natural circadian rhythm to exfoliate, renew, and restore. Powered by a blend of AHAs and BHA, this chemical peel treatment gently accelerates skin renewal, improving skin texture and reducing the appearance of scarring, hyperpigmentation and wrinkles while you sleep. Enhanced with OSMV™ Technology, the peel delivers active ingredients at the optimal time in sync with the skin's overnight circadian rhythm. As the final stage, it releases a blend of gotu kola to calm and soothe, eliminating the need for a neutralizing agent. In the evening, apply the Overnight Chronobiology Peel after cleansing. Use 1-2 times per week and allow the formula to dry for 10 minutes before applying a night cream. The micro-dosed release, made possible by our patented OSMV™ Technology, means no downtime is required the next day.
Multi-Defense Cream SPF 50 (60 doses) – A high-performance 100% mineral SPF 50 that protects against sun damage whilst working to correct existing signs of photoaging including hyperpigmentation, fine lines and wrinkles. The Multi-Defense Cream SPF 50 is the first SPF activated by UV light, designed to deliver protection when your skin needs it most. Apply the Multi-Defense Cream every morning as the final step in your skincare routine to keep your skin safe, hydrated, and luminous throughout the day.

Join our newsletter for 10% off your first order, plus early access to launches and The Noble Program updates.

Earn Loyalty points. Learn More
We stand by our science. Love it, or return it. Our Guarantee
Complimentary 2-Day Shipping in the US.
Need assistance? Talk to our skincare concierge. here



